Department of Molecular Physiology

Publications

• Hengl, T., Kaneko, H., Dauner, K., Vocke, K., Frings, S., Möhrlen, F. (2010)
  Molecular components of signal amplification in olfactory sensory cilia
  Proceedings of the National Academy of Sciences USA   107: 6052-6057   
  Open Access
   
  
• Frings, S. (2009)
  Chloride-based signal amplification in olfactory sensory neurons
  in Physiology and pathology of chloride transporters and channels in the nervous system.
  Alvarez-Leefmans, F.J. & Delpire, E. edts.. Academic Press (2009) pp. 413-424.
   
  
• Mayer, U., Küller, A., Daiber, P.C., Neudorf, I., Warnken, U., Schnölzer, M., Frings, S., Möhrlen, F. (2008)
  The proteome of rat olfactory sensory cilia
  Proteomics 9: 322-334   
   
  
• Mayer, U, Ungerer, N., Klimmeck, D., Warnken, U., Schnölzer, M., Frings, S., Möhrlen, F. (2008)
  Proteomic analysis of a membrane preparation from rat olfactory sensory cilia
  Chemical Senses   33: 145-162     
   
  
• Klimmeck, D., Mayer, U., Ungerer, N., Warnken, U., Schnölzer, M., Frings, S., Möhrlen, F. (2008)
  Calcium-signaling networks in olfactory receptor neurons.
  Neuroscience 151: 901-912      
   
  
• Kaneko, H., Möhrlen, F., Frings, S. (2006)
  Calmodulin contributes to gating control in olfactory calcium-activated chloride channels.
  Journal of General Physiology 127: 737-748    Abstract   PDF
  
  
• Kaneko, H., Putzier, I., Frings, S., Kaupp, U.B., Gensch, T. (2004)
  Chloride accumulation in mammalian olfactory sensory neurons.
  Journal of Neuronscience 24: 7931-7938    Abstract    PDF
  
  
• Bradley, J., Bönigk, W., Yau, K.-W.,and Frings, S. (2004)
  Calmodulin permanently associates with  rat olfactory CNG channels under native conditions
  Nature Neuroscience 7: 705-710     Abstract     PDF    News and Views
  
  
• Reisert, J., Bauer,P.J., Yau, K.-W., Frings, S. (2003)
  The Ca-activated Cl Channel and its control in Rat Olfactory Receptor Neurons.
  Journal of General Physiology 122: 349-363     Abstract     PDF
  
  
• Bradley, J., Reuter, D., Frings, S. (2001)
  Facilitation of calmodulin-mediated odor adaptation by cAMP-gated channel subunits.
  Science 294: 2176-2178     Abstract      Full Text     New nomenclature for cyclic nucleotide-gated channels      PDF
  
  
• Frings, S. (2001)
  Chemo-electrical signal transduction in olfactory sensory neurons of air-breathing vertebrates.
  Cellular and Molecular Life Science 58: 510-519     Abstract      PDF
  
  
• Bönigk, W., Bradley, J., Müller, F., Sesti, F., Boekhoff, I., Ronnett, G.V., Kaupp, U.B. and S. Frings (1999)
  The native rat olfactory cyclic nucleotide-gated channel is composed of three distinct subunits.
  Journal of Neuroscience 19: 5332-5347    Abstract     PDF
  
  
• Dzeja, C., Hagen, V., Kaupp, U.B. and S. Frings (1999)
  Ca²⁺permeation in cyclic nucleotide-gated channels.
  EMBO Journal 18: 131-144.     Abstract     PDF
  
  
• Reuter, D., Zierold, K., Schröder, W.H. and S. Frings (1998)
  A depolarizing chloride current contributes to chemo-electrical transduction in olfactory sensory neurons in situ.
  Journal of Neuroscience 18: 6623-6630   Abstract     PDF
  
  
• Müller, F., Bönigk, W., Sesti, F. and S. Frings (1998)
  Phosphorylation of mammalian olfactory cyclic nucleotide-gated channels increases ligand sensitivity.
  Journal of Neuroscience 18: 164-173.   Abstract     PDF
  
  
• Frings, S. (1993)
  Protein kinase C sensitizes olfactory adenylate cyclase.
  Journal of General Physiology 101: 183-205.    Abstract    PDF
  
  
• Frings, S. and B. Lindemann (1992)
  Noninvasive recording from sensory cilia of olfactory receptor neurons maintained in situ in the isolated amphibian olfactory mucosa.
  In: Practical Electrophysiological Methods. Kettenmann, H.and R. Grantyn, eds. Wiley-Liss, New York. pp. 88-92.   Abstract
  
  
• Frings, S., Lynch, J. and B. Lindemann (1992)
  Properties of cyclic nucleotide-gated channels mediating olfactory transduction: activation by cyclic nucleotides, ion selectivity and channel blockage.
  Journal of General Physiology 100: 45-67.    Abstract   PDF
  
  
• Frings, S., Benz, S. and B.Lindemann (1991)
  Current recording from sensory cilia of olfactory receptor cellsin situ. II. Role of mucosal Na⁺,K⁺,and Ca²⁺ ions.
  Journal of General Physiology 97: 725-747.    Abstract   PDF
  
  
• Frings, S. and B. Lindemann (1991)
  Current recording from sensory cilia of olfactory receptor cells in situ. I. The neuronal response to cyclic nucleotides.
  Journal of General Physiology 97: 1-16.    Abstract    PDF
  
  
• Frings, S. and B. Lindemann (1990)
  Response of olfactory receptor cells, isolated and in situ, to low concentrations of odorants.
  In: Chemosensory Information Processing, D. Schild,ed., Springer Verlag, Berlin. pp. 1-8.
  
  
• Frings, S. and B. Lindemann (1990)
  Single unit recordings from olfactory cilia.
  Biophysical Journal 57: 1091-1094    Abstract
  
  
• Frings, S. and B. Lindemann (1988)
  Odorant response of olfactory receptor cells is blocked by amiloride.
  Journal of Membrane Biology 105: 233-243    Abstract