Department of Molecular Physiology


Ca-activated Cl-channels
  • Hahn, A., Salomon, J.J., Leitz, D., Feigenbutz, D., Korsch, L., Lisewski, I., Schrimpf, K., Millar-Büchner, P., Mall, M.A., Frings, S., Möhrlen F. (2018)
    Expression and function of Anoctamin 1/TMEM16A calcium-activated chloride channels in airways of in vivo mouse models for cystic fibrosis research.
    Pflügers Archiv - European Journal of Physiology   doi: 10.1007/s00424-018-2160-x   
  • Neureither, F., Stowasser, N., Frings, S., Möhrlen F. (2017)
    Tracking of unfamiliar odors is facilitated by signal amplification through anoctamin 2 chloride channels in mouse olfactory receptor neurons.
    Physiolological Reports   5: e13373   Open Access
  • Neureither, F., Ziegler, K., Pitzer, C., Frings, S., Möhrlen, F. (2017)
    Impaired motor coordination and learning in mice lacking anoctamin 2 calcium-gated chloride channels.
    Cerebellum    doi: 10.1007/s12311-017-0867-4   Open Access
  • Hahn, A., Faulhaber, J., Srisawang, L., Stortz, A., Salomon, J.J., Mall, M.A., Frings, S., Möhrlen F. (2017)
    Cellular distribution and function of ion channels involved in transport processes in rat tracheal epithelium.
    Physiolological Reports   5: e13290   Open Access
  • Zhang, W., Schmelzeisen, S., Parthier, D., Frings, S., Möhrlen, F. (2015)
    Anoctamin calcium-activated chloride channels may modulate inhibitory transmission in the cerebellar cortex
    PLOS ONE   10(11):e014216       Open Access
  • Vocke, K., Dauner, K., Hahn, A., Ulbrich, A., Broecker, J., Keller, S., Frings, S., Möhrlen, F. (2013)
    Calmodulin-dependent activation and inactivation of anoctamin calcium-gated chloride channels.
    Journal of General Physiology    142: 381-404.   
  • Dauner, K., Möbus, C., Frings, S., Möhrlen, F. (2013)
    Targeted expression of anoctamin calcium-activated chloride channels in rod photoreceptor terminals of the rodent retina
    Investigative Ophthalmology and Visual Science    54: 3126-3136.   
  • Dauner, K., Lißmann J., Jeridi, S., Frings, S., Möhrlen, F. (2012)
    Expression patterns of anoctamin 1 and anoctamin 2 chloride channels in the mammalian nose
    Cell and Tissue Research    347: 327-341      
  • Hengl, T., Kaneko, H., Dauner, K., Vocke, K., Frings, S., Möhrlen, F. (2010)
    Molecular components of signal amplification in olfactory sensory cilia
    Proceedings of the National Academy of Sciences USA    107: 6052-6057   
    Open Access
  • Frings, S. (2009)
    Chloride-based signal amplification in olfactory sensory neurons
    in Physiology and pathology of chloride transporters and channels in the nervous system.
    Alvarez-Leefmans, F.J. & Delpire, E. edts.. Academic Press (2009) pp. 413-424.
  • Klimmeck, D., Daiber, P.C., Brühl, A., Baumann, A., Frings, S., Möhrlen, F. (2009)
    Bestrophin 2 - an anion channel associated with neurogenesis in chemosensory systems
    Journal of Comparative Neurology     515: 585-599     
  • Kaneko, H., Möhrlen, F., Frings, S. (2006)
    Calmodulin contributes to gating control in olfactory calcium-activated chloride channels.
    Journal of General Physiology 127: 737-748    Abstract   PDF

  • Kaneko, H., Putzier, I.,  Frings, S., Kaupp, U.B., Gensch, T. (2004)
    Chloride accumulation in mammalian olfactory sensory neurons.
    Journal of Neuronscience 24: 7931-7938    Abstract    PDF

  • Reisert, J., Bauer,P.J., Yau, K.-W., Frings, S. (2003)
    The Ca-activated Cl Channel and its control in Rat Olfactory Receptor Neurons.
    Journal of General Physiology 122: 349-363     Abstract     PDF

  • Kaneko, H., Putzier, I., Frings, S., Gensch, T. (2002)
    Determination of intracellulaer chloride concentration in dorsal root ganglion neurons by fluorescence lifetime imaging.
    Current Topics in Membranes 53: 167-189

  • Frings, S., Reuter, D. and S.J. Kleene (2000)
    Neuronal Ca2+-activated Cl- channels - homing in on an elusive channel species.
    Progress in Neurobiology 60: 247-289.    Abstract     PDF

  • Reuter, D., Zierold, K., Schröder, W.H. and S. Frings (1998)
    A depolarizing chloride current contributes to chemo-electrical transduction in olfactory sensory neurons in situ.
    Journal of Neuroscience 18: 6623-6630   Abstract      PDF

Ca-activated Cl-channels

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